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The magnitude of the association between psoriasis and depression has been evaluated, but not that between psoriasis and anxiety. The aim of this systematic review and meta-analysis was to examine the prevalence and odds of anxiety disorders and symptoms in patients with psoriasis. A total of eligible articles were identified. There were insufficient studies assessing other anxiety disorders to be able to draw any conclusions on their true prevalence.
Case-control studies showed a positive association between psoriasis and unspecified anxiety disorder odds ratio 1. All meta-analyses revealed an important heterogeneity, which could be explained in each case by methodological factors.
The results of this study raise the necessity of screening for the presence of anxiety disorders, as previously recommended for depressive disorders, in patients with psoriasis and, if necessary, to refer such patients for evaluation by a mental health professional and appropriate treatment.
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JAMA Dermatol ; Association between hidradenitis suppurativa, depression, anxiety, and suicidality: a systematic review and meta-analysis. The prevalence and odds of anxiety and depression in children and adults with hidradenitis suppurativa: systematic review and meta-analyses. Psychiatric comorbidity in chronic urticaria patients: a systematic review and meta-analysis. Clin Transl Allergy ; 9: American Psychiatrist Association.